东北大学学报（自然科学版）

东北大学学报(自然科学版) ›› 2008, Vol. 29 ›› Issue (5): 625-628.DOI: -

• 论著 • 上一篇    下一篇

基于摄氧率的分批发酵过程阶段辨识

杨强大;王福利;常玉清;张璇;   

  1. 东北大学流程工业综合自动化教育部重点实验室;东北大学流程工业综合自动化教育部重点实验室;东北大学流程工业综合自动化教育部重点实验室;沈阳燃气股份有限公司 辽宁沈阳110004;辽宁沈阳110004;辽宁沈阳110004;辽宁沈阳110005
  • 收稿日期:2013-06-22 修回日期:2013-06-22 出版日期:2008-05-15 发布日期:2013-06-22
  • 通讯作者: Yang, Q.-D.
  • 作者简介:-
  • 基金资助:
    国家重点基础研究发展规划项目(2002CB312200)

OUR-based identification of growth phases in batch fermentation

Yang, Qiang-Da (1); Wang, Fu-Li (1); Chang, Yu-Qing (1); Zhang, Xuan (2)   

  1. (1) Key Laboratory of Integrated Automation of Process Industry, Northeastern University, Shenyang 110004, China; (2) Shenyang Gas Co. Ltd., Shenyang 110005, China
  • Received:2013-06-22 Revised:2013-06-22 Online:2008-05-15 Published:2013-06-22
  • Contact: Yang, Q.-D.
  • About author:-
  • Supported by:
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摘要： 针对发酵阶段难以在线辨识的问题,提出了一种基于摄氧率的需氧型发酵过程阶段辨识方法.利用在线可测的摄氧率对处于特定发酵阶段的比生长率进行预估,再利用比生长率的预估值进行发酵阶段的在线辨识.由于摄氧率极易在线获得,所以这种辨识方法非常容易实现.针对诺西肽发酵过程,利用所提出的方法进行发酵阶段的在线辨识,阶段辨识结果与过程知识相一致.这不仅可以增进对当前生产状况的了解,而且可以指导适时地实施各种控制策略,从而提高产品的质量.

关键词: 阶段辨识, 比生长率, 摄氧率(OUR), 耗氧分批发酵, 诺西肽

Abstract: A simple identification based on the OUR (oxygen uptake rate) is proposed to rise above the difficulty of on-line classification of mycelia growth phases in aerobic fermentation process. The specific growth rate at a certain growth phase is pre-estimated using the on-line measurable OUR, then the on-line identification of growth phases is available to carry out in accordance to the pre-estimated value of specific growth rate. Such an identification is very easy to implement since the OUR can be obtained on-line. This method has been applied to Nosiheptide fermentation process, and the identification results are consistent with the actual process. It will not only deepen the understanding of the present situation of production, but also guide the timely implementation of various control schemes to improve the quality of products.

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