东北大学学报:自然科学版 ›› 2020, Vol. 41 ›› Issue (11): 1570-1576.DOI: 10.12068/j.issn.1005-3026.2020.11.008

• 信息与控制 • 上一篇    下一篇

CTA图像冠状动脉开口层与开口点的全自动定位方法

罗洋1,2, 齐林1, 徐礼胜1,3   

  1. (1. 东北大学 医学与生物信息工程学院, 辽宁 沈阳110169; 2. 鞍山师范学院 高等职业技术学院, 辽宁 鞍山114056; 3. 东北大学 教育部医学影像计算重点实验室, 辽宁 沈阳110169)
  • 收稿日期:2020-01-20 修回日期:2020-01-20 出版日期:2020-11-15 发布日期:2020-11-16
  • 通讯作者: 罗洋
  • 作者简介:罗洋(1975-),男,辽宁鞍山人,东北大学博士研究生; 徐礼胜(1975-),男,安徽安庆人,东北大学教授,博士生导师.
  • 基金资助:
    国家自然科学基金资助项目(61773110); 沈阳东软智能医疗科技研究院有限公司开放课题基金资助项目(NRIHTOP1801).

Fully Automatic Location Method of Ostial Layers and Points of Coronary Arteries for Computed Tomographic Angiographic Images

LUO Yang1,2, QI Lin1, XU Li-sheng1,3   

  1. 1. School of Medicine & Biological Information Engineering, Northeastern University, Shenyang 110169, China; 2. School of Advanced Vocational Technology, Anshan Normal University, Anshan 114056, China; 3. Key Laboratory of Medical Image Computing, Ministry of Education, Northeastern University, Shenyang 110169, China.
  • Received:2020-01-20 Revised:2020-01-20 Online:2020-11-15 Published:2020-11-16
  • Contact: XU Li-sheng
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摘要: 首先在基于多条件区域增长和解剖结构的基础上通过圆度的变化确定左冠脉开口层,并在指定范围内确定左冠脉开口点;其次计算升主动脉中心和右冠脉开口范围,利用距离曲线的波峰和波谷,并结合解剖结构的特征来确定右冠脉开口层和开口点.该方法中的各种参数得到了统计学验证.最后对57个对象进行测试,左右冠脉开口层定位准确率分别达到98.2%和96.5%.定位的左右冠脉开口点到金标准点的平均距离分别是(1.22±0.37)mm和(1.76±0.49)mm.实验验证了该方法的有效性.

关键词: 左冠脉开口, 右冠脉开口, 升主动脉, 区域增长, 距离曲线

Abstract: Firstly, the ostial layer of the left coronary arteries by change of roundness is determined on the basis of multi-condition region growth and the anatomic structure, and the ostial point of the left coronary arteries within the specified range is determined.Secondly, the ascending aorta center and the ostial range of the right coronary arteries are calculated, and the peaks and valleys of the distance curve combined with the features of the anatomic structure are utilized to determine ostial layer and point of the right coronary arteries. The parameters of the proposed method are statistically verified. Finally, 57 subjects are tested. The accuracy of locating the ostial layers of left and right coronary arteries are 98.2% and 96.5%, respectively. The average distances between located ostial points of left and right coronary arteries and the ground truth are (1.22± 0.37)mm and (1.76± 0.49)mm, respectively. The experiments demonstrate the validity of the proposed method.

Key words: ostia of left coronary arteries, ostia of right coronary arteries, ascending aorta, region growth, distance curve

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