Abstract: Based upon fractal theory, a fractal supply chain serving the functions of self-similarity, self-organization and self-optimization is proposed for high-uncertainty demands of customers of an e-Biz company under networked manufacturing so as to balance dynamically the flexibility and stability in building its supply chain and relevant operation. Describes the conception of fractal supply chain. The nested structure of e-Biz's supply chain and functional module are constructed. Then, the dynamic decision-support models of analyzer and resolver are developed. The numerical example shows that the fractal supply chain can deal well with the complicated relationship between different supply chain's members and control efficiently the uncertainty of supply chain management, thus adapting dynamically to the management system which requires agility, integration and systematization.