Abstract: Considering the viscoelastic coefficient and pulsating flow factors, the nonlinear fluid-structure interaction vibration differential equation of the hydraulic pipe was established by using the Newton method, and the dimensionless equation was carried out. The dimensionless equation was discretized with the Galerkin method by the beam model for lateral bending vibration mode function. Effects of the fluid pressure, fluid velocity and axial force on vibration characteristics of the aero-engine hydraulic pipe were simulated by the Matlab and Mathematica softwares. The experimental results agree well with the theory.