The Analysis of Different Kinds of Adaption Mechanisms of Neuron Model under External Alternating Electric Field

Abstract

Abstract: External electric field has an effect on neuronal dynamics and neuronal information processing, but its mechanism is unknown. Spike-frequency adaption is a prominent feature of neuronal dynamics that plays an important role in neuronal information processing. In order to investigate the different mechanisms of spike-frequency, based on the leaky integrate-and-fire model (LIF model), two kinds of modified LIF models under external alternating electric field are established in this paper. By analyzing the spiking trains, the curves of the onset spike frequency and the curves of the spike frequency of the steady state, different effects induced by the adaption under external alternating electric field are shown in this paper. The LIFAC shifts the frequency curves to higher inputs without affecting its slope. On the other hand, the LIFDT has a divisive effect on the frequency curves. The spike frequency of the steady state is linear under the external alternating electric field. The correlation and the variability between consecutive interspike intervals (ISIs) are also studied to furthermore illustrate the effects of external alternating electric field on different kinds of adaption mechanisms.

Key words: Spike-Frequency Adaption, External Alternating Electric Field, the LIF Model, Interspike Interval, Correlation

References

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