Abstract: Disease is not only a research object of medical science， but also an important content of literary description. In modern Chinas little city novels， disease has become a carrier by surpassing the concrete physiological symptoms and medical significance. The disease narration in modern Chinas little city novels is characterized by multiple directivity， which has both physical reflection and metaphysical thinking. In these novels， the disease narration is placed in a broad social context and the disease description includes both social and ideological connotations of that specific time. The disease narration is not only the description of individual physical symptoms， but also the revelation of Chinas social characteristics in sickness. The disease of the people and the decline of the nation have become a representation and isomorphism， which express the writers more profound reflection and questioning on the social realities and current situations of the nation.

Key words: little city novel, disease narration, social reality, current situation of the nation, representation