基于CFD的血管病变部位血流流变特性分析

doi:10.12068/j.issn.1005-3026.2020.01.026

东北大学学报:自然科学版 ›› 2020, Vol. 41 ›› Issue (1): 148-152.DOI: 10.12068/j.issn.1005-3026.2020.01.026

• 生物工程 • 上一篇

基于CFD的血管病变部位血流流变特性分析

鹿晔，张树生

(山东大学能源与动力工程学院，山东济南250061)

收稿日期:2019-04-29 修回日期:2019-04-29 出版日期:2020-01-15 发布日期:2020-02-01
通讯作者: 鹿晔
作者简介:鹿晔(1986-)，男，山东济南人，山东大学博士研究生; 张树生(1963-)，男，山东济南人，山东大学教授，博士生导师.
基金资助:
国家自然科学基金青年基金资助项目(51806123)；山东省自然科学基金资助项目(ZR2018BEE025).

Rheological Characteristics Analysis of Blood Flow at the Site of Vascular Lesion Based on CFD

LU Ye， ZHANG Shu-sheng

School of Energy and Power Engineering， Shandong University， Jinan 250061， China.

Received:2019-04-29 Revised:2019-04-29 Online:2020-01-15 Published:2020-02-01
Contact: ZHANG Shu-sheng
About author:-
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摘要/Abstract

摘要： 为探究血管病变对血流流动特性的影响，研究了血管结构改变前后血流流动特性的改变.提出了一种对血管病变前后的血流流场进行对比研究分析的方法，利用断层扫描数据建立几何模型，用Geomagic Studio将病变血管复原成为发生病变前的形状，并基于弹性血管中血流脉动的力学特性，使用ANSYS软件对采用牛顿流体力学模型的分叉部位血流流场进行数值模拟.模拟结果显示病变组织部位受到更大的切应力影响，而在病变组织远心端产生了明显的流速低和切应力低的二次流动和更大的血压压差，这些流体特性会对血管进一步病变产生重要影响.

关键词: 动脉粥样硬化, 血流动力学, 动脉分叉, 计算流体力学, 血管病变

Abstract: In order to study the influence of vasculopathy on hemodynamic characteristics of blood flow， the blood flow characteristics were studied before and after changes took place in blood vessel structure. A method of comparative study focusing on the blood flow characteristics in artery with and without atherosclerosis was proposed. The geometry model was established based on data taken from tomography scan. Geomagic Studio was used to convert the pathological blood vessel model back into healthy vessel model. The blood flow characteristics were investigated based on the condition of pulsatile blood stream flowing in elastic vessel. The blood flow field in bifurcation region was simulated with ANSYS software adopting Newtonian mechanical model. Result indicates that the lesion site on vessel wall suffers larger shear stress. Secondary flow occurs in the distal end of lesion site with low flow velocity， low shear stress and higher pressure difference， which indicates that the atherosclerosis will be further affected.

Key words: atherosclerosis, hemodynamics, artery bifurcation, computational fluid dynamics(CFD)；vasculopathy

中图分类号:

鹿晔，张树生. 基于CFD的血管病变部位血流流变特性分析[J]. 东北大学学报:自然科学版, 2020, 41(1): 148-152.

LU Ye， ZHANG Shu-sheng. Rheological Characteristics Analysis of Blood Flow at the Site of Vascular Lesion Based on CFD[J]. Journal of Northeastern University Natural Science, 2020, 41(1): 148-152.

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基于CFD的血管病变部位血流流变特性分析

Rheological Characteristics Analysis of Blood Flow at the Site of Vascular Lesion Based on CFD

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