Journal of Northeastern University(Natural Science) ›› 2022, Vol. 43 ›› Issue (7): 944-950.DOI: 10.12068/j.issn.1005-3026.2022.07.005

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U-Net CSF Cells Segmentation Based on Attention Mechanism

DAI Yin1,2, LIU Wei-bin1,2, DONG Xin-yang3, SONG Yu-meng1,2   

  1. 1. College of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China; 2. Engineering Center on Medical Imaging and Intelligent Analysis, Ministry of Education, Northeastern University, Shenyang 110169, China; 3.School of Computing, University of York, Yorkshire YO10 5DD, UK.
  • Published:2022-08-02
  • Contact: DAI Yin
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Abstract: In order to solve the problem that part of the cell membrane in the pathological images of CSF (cerebrospinal fluid) is blurred and this is difficult to be distinguished from the image background. The U-Net based on attention mechanism is proposed to segment pathological images of CSF automatically. Attention mechanism is added to deep learning network to locate cells, suppress irrelevant information, improve semantic feature expression, and further improve the accuracy of cell segmentation. The datasets are preprocessed by mirroring and rotation. VGG16 pre-training model is used for transfer learning. Cross entropy is combined with Dice loss as Loss function which is validated in CSF clinical images and open dataset 2018 Data Science Bowl and compared with Otsu, PSPnet, Segnet, DeeplabV3+, U-Net. The results show that the proposed method is superior to other segmentation methods in all indexes.

Key words: CSF test; cell segmentation; attention mechanism; deep learning; U-Net model

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