Abstract:

Determining key injection parameters of bone cement， such as volume， pressure and angle， in percutaneous vertebroplasty still largely relies on empirical judgment， and they have a critical role in preventing leakage and related complications. An advanced simulation framework that integrated a multiphase non-Newtonian fluid model was introduced. The framework employed a Voronoi-based biomimetic bone representation to predict cement flow behavior within trabecular structures， enabling high-fidelity visualization and analysis of cement dispersion under varying operating conditions. Experimental results demonstrate the framework’s potential value in preoperative planning optimization， surgical training assistance， and leakage risk assessment. For preoperative use， it can assist clinicians in rehearsing injection procedures and refining operation strategies； in training scenarios， it can simulate cement dispersion patterns under different parameter settings， thereby helping novice surgeons understand procedural logic； furthermore， its capability to predict leakage risks holds promise for providing technical support to improve clinical surgical safety.

Key words: medical visualization, bone filling simulation, multiphase non-Newtonian fluid modeling, bone cement