Abstract: The problem of fault-tolerant control for delta operator systems based on circular regional pole assignment, which is defined as D-stable robust fault-tolerant control, is studied. By the use of linear matrix inequalities, the two sufficient conditions that the poles of the closed-loop system are assigned in a specific circular region and the nominal system possessing integrity against actuator failure are presented. Then, by means of algebraic Riccati equations, the robust fault-tolerant control problem for uncertain delta operator systems based on regional pole assignment is discussed, with the design methods for D-stable fault-tolerant controller and D-stable robust fault-tolerant controller both given. The proposed method can unify some previous related results of continuous and discrete time systems into the delta framework.