Abstract: Based on the different of solubilities of alkali metal chlorides in alcohol, the highly purified lithium chloride with low sodium/potassium contents was prepared for the first time by alcohol extraction process. The results showed that calcium content in mass fraction can be controlled lower than (10-15) × 10^-6 after decalcification by adding 0.6% lithium oxalate, meanwhile, the sodium and potassium contents can be lower than 40 × 10^-6 and 5 × 10^-6, respectively, when filtering the solution 2 times and the liquid to solid ratio 8.5. Such a result means that the alcohol extraction is an effective way to remove sodium and potassium in preparing highly purified lithium chloride.