Abstract: The features and transportation cost structures of three transportation modes for an enterprise combining production with distribution are comparatively analyzed, including independent running, 3rd party logistics and vehicle leasing. Under conditions that the distribution networks is composed of a single supplier, multiple retailers, multiple products and multiple direct delivery, the relationships between the total costs resulting from different optimum solutions to the transportation modes as above are analyzed combining different values of different parameters, especially how the change in parameters affect the total costs when the vehicle leasing was done in an outsourcing way. The result show that the influence of loading charge in an outsourcing way on the total cost is greater than that of any parameters else.