Abstract: The frontal and side impact of a car were simulated and the whole body response and injury of passanger thus caused were evaluated on computer. FEA models were developed for the whole car in which the space occupied by the 50th percentile Hybrid III dummy and safety-belt restraint system. According to the basic principle of dynamic non-linear FEM, an equation describing the impact process and FEA discretization equation are given. The frontal and side impact of the integrated system of the whole car is numerically simulated and analyzed by the software LS-DYNA, then the time curves of displacement, speed and acceleration for car during impact are solved, as well as the effect of the main energy-absorbing parts, the energy/force transmitting path and the injury level of dummy due to impact. Simulation results revealed that such a simulation will predict not only the crashworthiness of the car but also the passengers' response and injury level comparatively accurately during its collision. It will be of significance to reducing the number of impact tests and expediting the R and D of new type/model of cars.