Abstract: 9 groups of high-performance concrete specimens were designed for orthogonal test where each of the 3 factors was at 3 levels with an L9(3⁴) orthogonal table set out. The three factors/levels were the mixing at artificial, mechanical and overtime levels; the vibrating at artificial, mechanical and non-vibrating levels and the curing at natural, standard and humidity-insulated levels. The compressive strength tests for the 9 groups of high-performance concrete specimens were carried out for 14 days and 28 days separately, then the differential analysis and variance analysis were made for the orthogonal test results. The analyses indicated that among the three influencing factors on the compression strength of the high-performance concrete the mixing, curing and vibrating are ranked the first, second and third, respectively, and the optimal modes(levels) are the overtime mixing, non-vibrating and humidity-insulated curing.