Abstract: Transverse load distribution of large-angle hinged skew slab bridge was studied, and the method to calculate the influence line of transverse load distribution with an empirical formula was put forward. In order to establish a reliable numerical model, shear-flexible grillage method was adopted, then organic glass model was made to verify the reasonableness of the numerical model. Numerical models of hinged skew slab bridges with different slabs, different skew angles were established to get the empirical formulas of the influence line of transverse load distribution. Finally, the reliability of the empirical formulas was validated by theoretical calculation.