Abstract: Based on previous jointed model tests and numerical simulation studies, several groups of material compression tests were designed on joint models with holes, and model experimental processes were simulated with particle flow code software (PFC2D). Tallies of the stress-strain curve and numerical simulation curve were taken as selection criterion of PFC mesomechanics parameters in the model experiment. After that, the failure process of jointed rockmass with holes was simulated by the mesomechanics parameters to reappear. The failure process and mechanism of jointed rockmass with holes are discussed. The entire process was divided into four stages, including the linear elastic stage, the early crack stage, the peak stage, and post-peak stage. This failure mechanism can reasonably predict the failure mode of the actual engineering and evaluate the stability of engineering rockmass.