Abstract: Using single factor and orthogonal test designs, the factors affecting dyeing wastewater treatment were studied using CWO technology and a Cu-Fe-La/FSC catalyst. Biodegradability of water samples was investigated under optimal operating conditions. The decolorization rates of water samples increased with increases in catalyst amount, reaction temperature, reaction pressure and reaction time, while water sample decolorization rates decreased with increasing solution dilution. Water sample treatment was affected, from most to least, by the following factors: reaction temperature, reaction time, catalyst amount, reaction pressure, and concentration of incoming wastewater. Use of the CWO method significantly increased biodegradability of printing and dyeing wastewater, and B/C of the water samples increased by 30.5%.