Abstract: To solve the problems that mining tunnels along vein often destroyed by the poor stability of surrounding rock of metallic mineral deposit and ground pressure, the distribution characteristics and changes of ground stress in rock mass due to different mining methods were studied numerically. The mechanism of stress field migration controlled by depressurization was discussed to provide theoretical basis for the optimization of structural parameters of stopes. The results showed that mining ore-body will induce ground stress re-distribution in rock mass nearby, and increasing the span or decreasing the height of goaf can lead to obvious vertical stress drop so as to implement depressurized mining. For the medium-thick ore-body of a copper mine, the numerical results showed that when the roadway is located 6m away from the footwall of the ore-body, the vertical stress in the vicinity of roadway is decreased by 18% after mining, which can meet the requirements of depressurized mining and economic benefits.