Abstract: The newly developed Ni-based alloy containing a certain amount of Al nanopowder was taken to prepare a ceramic-phase coating on Cu-Cr alloy surface through pulse laser-induced reaction in-situ. The microstructure morphology and coating mechanism was studied experimentally. The result showed that under condition of optimized process parameters of the laser-induced reaction in-situ, a bonding interface forms between the substrate and coating, which consists of both coating and substrate elements in form of refined grains. The Al nanopowder can offer more energy to promote the formation of coating, while the cladding structure is reinforced by the ceramic grains whose size are less than 10 μm. The Al nanopowder/RE oxides added in coating serve the function of reducing the formation of cracks/pores. As a result, the average microhardness of the coating is 340 HV instead of 85 HV which is that of the substrate without coating.