Abstract: Anaerobic hydrolysis reactor and UNITANK reactor are integrated into one to form the anaerobic hydrolysis-UNITANK process so as to treat the pharmaceutical wastewater. The anaerobic hydrolysis is mainly used to hydrolyze the primary organic matters in wastewater for preliminary degradation. Then, the effluent from the anaerobic hydrolysis reactor inters into the UNITANK reactor to degrade organic matters further. The effluent treated by the anaerobic hydrolysis-UNITANK process into the Aeration of Biography Filter (BAF) tank to degrade organic matters once more so as to purify the wastewater. The optimum process parameters and conditions were found through experiments, the optimum hydrolytic temperature is 25°C-30°C and 20°C for anaerobic hydrolysis reactor and UNITANK reactor, respectively, and the optimum retention time is 12 hr and 90 hr for anaerobic hydrolysis reactor and UNITANK reactor, respectively.