Abstract: Aiming at the present situation that the ground pressure acts so intensively in Hongtoushan copper mine, a microseismic monitoring system was developed by optimizing the layout of sensors with a three-dimensional geological model developed relevantly to monitor realtime continuously how the ground pressure acts. The monitoring result is compared with the actual seismic source through blasting and it shows that the locating error is less than 5 m which is highly accurate in locating seismic source through a microseismic monitoring system. Capturing microseismic information from ground pressure activities and then locating the seismic source is proved of significance to forecasting dynamic disaster in deep mine.