Abstract: In order to reasonably use the boron-concentrate ore from magnetic separation of Liaoning ludwigite, the raw samples were roasted with ammonium sulfate. Then the roasted materials were separated by filtration after being dissolved into water. The boron-rich solution was used to recover boron acid while the remaining residue was used as a raw material for SiO2 and MgO recovery. Single factor experiments were conducted to study the influences of roasting temperature, roasting time and ammonium/ore ratio on the leaching rate of B2O3. The reasonable conditions obtained by orthogonal test are: roasting temperature of 400°C, roasting time of 90min, and ammonium/ore ratio of 1.6. Under such conditions, the leaching rate of B2O3 is over 85%. The chemical composition analysis and XRD results show that, this method can extract the majority of soluble boron from boron-concentrate ore, and thereby realize the eco-friendly comprehensive utilization of boron-concentrate ore.