Abstract: The debate over whether genetic engineering technology should be used for human enhancement has existed for years. The rapid development of genome-editing technologies dedicated to precision prevention， precision diagnosis and precision treatment has once again aroused people's attention to “enhancement” and “perfection” technologies. The American philosopher Sandel is clearly “against perfection”， who holds that human enhancement based on genome-editing technologies undermines the moral status of nature， weakens the respect for human beings， breaks the balance between goodness and power， and thus brings social injustice. From the perspective of communitarianism and Aristotle's virtue ethics， Sandel advocates the harmonious， moderate and natural use of technologies. Sandel's “against perfection” has important enlightenment for today's analysis and research on the ethical issues of genome-editing technologies.

Key words: Michael Sandel, genome-editing technology, against perfection, communitarianism, ethics